Kittens can be given anticlotting and antihemophilic factor (AHF) as soon as they are born. If the kitten has a bleeding disorder called thrombocytopenia, it will need an injection of recombinant activated protein C (rAPC). APC is a bispecific monoclonal antibody that binds to both factors VIII and IX, which clot blood after a cat or dog receives a blood transfusion. This helps prevent clotting in cats who have inherited deficiencies of these factors from their mother. For cats with mild defects, this treatment may provide longer survival time during periods of stress such as surgery or stressful transport. In most instances, however, treating anemic kittens with APC is not necessary because most kittens without severe deficiency already produce enough coagulation factor VIII from either the liver or from their bone marrow cells.
What causes feline hemolytic disease?
The source for this problem must be identified before determining what type of medication to use to treat it successfully:
Infectious: FVRCP-positive bacteria present on the surface membranes that line red blood cells stimulate production by platelets of enzymes that break down proteins into small fragments called peptides—the same mechanisms used by streptococci and staphylococci infecting humans; thereby causing hemolysis similar to those caused by bacterial infections such as brucellosis and rickettsiosis; hematologic reactions occur frequently