What Is Not A Typical Finding In Fading Puppy And Kitten Syndrome?

Fading puppy and kitten syndrome is not detected or diagnosed by the usual tests for severe hypothyroidism. These include blood thyroid levels, T4 to T3 conversion ratio, free thyroxine index (fTI), total thyroxine index (TQI), thyroid-stimulating hormone, reverse t3 antibodies and faecal urobilinogen test. All of these are normal in this condition . It appears that there are no specific ophthalmic findings that distinguish fading puppy and kitten syndrome from other causes of blindness. Why then do patients recover their sight? The answer lies with an underlying global metabolic dysfunction caused by either primary hypothyroidism or secondary starvation. It could also be termed metabolic bone disease as it is accompanied by skeletal abnormalities such as thin bones, osteoporosis , fractures etc..

How does fading puppy & kitten syndrome develop?

The exact cause of FKS remains unknown but multiple factors have been associated with its development including genetics, diet influence(both poor nutrition during gestation/lactation) , low body temperature due to exposure to cold temperatures at birth etc.. There is a strong association between FKS and congenital hypothyroidism which may account for some cases being inherited i f the patient’s parents were both carriers of the disease who passed on one copy each chromosome per generation . However “environmental” influences must play an important role because families who live far apart often have dogs with differing susceptibility levels